A′PIOL

(-pe-ōle; or -ŏl). Prep. The soft alcoholic extract of parsley-seed is either digested or agitated for some time with ether; after sufficient repose in a cool place, the ethereal solution is decanted, and the ether removed by distillation; the residuum is purified by solution in rectified spirit, and agitation first with a little litharge, and next with animal charcoal; after which the spirit is removed by distillation from the filtered solution. Prop., . A yellow, oily, non-volatile liquid, having a peculiar smell, and a highly disagreeable taste; soluble in alcohol, ether, and chloroform; insoluble in water; and coloured red by strong sulphuric acid. Sp. gr. 1·078. In small doses it excites the pulse and nervous system; and in larger ones it causes headache, giddine , vertigo, . It is said to be powerfully febrifuge, and has been highly extolled by MM. Joret and Homalle as a substitute for quinine in intermit tents. [74] It has also been found useful in intermittent neuralgias and the nocturnal sweats of phthisis. Dose , 5 to 15 drops, in capsules. [74] According to Drs G. O. Rees and A. S. Taylor, 66 out of 116 cases were cured by it in their practice; but according to the French Commi ion, the cures are only 42%, and in many of these only temporary.