Nogu'chi test

[Hideyo Noguchi, Japanese bacteriologist in New York, *i876.] i. A test for tabes or general paralysis, depending upon a specific albumin reaction of the spinal fluid; o I c.c. of the spinal fluid to be tested is placed in a test-tube "whose diameter is i cm. or le . To this is added 0.5 c.c. of a 10 per cent, solution of butyric acid. The tube is now heated until the fluid is bubbling, and while still hot o i c.c. of a normal (4 per cent.) solution of sodium hydrate is added. In nearly all spinal fluids an opalescence or cloud occurs, but in the spinal fluid of general paralysis the cloud soon separates into a definite flocculence is characteristic,.t. test for syphilis, a modification of the Wa ermann method: The antigen is a lipoid substance extracted from the liver and heart; human corpuscles instead of sheep's corpuscles are used, and the hemolytic ambocepter is obtained by immunizing rabbits against normal human erythrocytes. The hemolytic ambocepter and antigen are preserved by soaking filter paper and drying. The antigen filter paper is placed ift human serum, guinea-pig's serum is added and both are diluted with isotonic salt solution; after this has stood a definite time at incubator temperature the hemolytic amboceptor paper