Fibrin

(fi/-brin). A native albumin or proteid, a substance that, becoming solid in shed blood, plasma, and causes coagulation of these fluids. It then exists in the shape of innumerable, exce ively delicate, closely packed, microscopic, doubly refractive fibrils, entangling the blood-corpuscles, as in a spider's web, and with them forming the blood-clot or placenta sanguinis. Fibrin forms about 0. 2 per cent, of the blood and is insoluble in water and ether. It is changed into syntonin by dilute hydrochloric acid. F. -ferment, a ferment obtainable from blood-serum after clotting has occurred. It does not exist in the living, circulating blood. Its activity is destroyed by heating to 700 F. Fibrin at i on. The acquirement of an abnormal amount of fibrin.