Sclerosis

(skle-ro' -sis). which consists e entially in an overgrowth of the proce con nective ti ue of an organ. The term is applied chiefly to the nervous system and the arteries. 2. In biology, the hardening of a plant cell-wall by the formation of lignin; the induration of a normally soft ti ue. S., Amyotrophic Lateral, a combination of chronic anterior poliomyelitis with lateral sclerosis. The symptoms are in the main wasting of the muscles and a spastic condition of the limbs, with exaggeration of the reflexes. The disease is prone to end fatally by involvement of the medulla oblong at a. S., Annular, a chronic myelitis, in which the sclerosis extends about the cord like a ring. S., Arterio-. See S., Atrophic, sclerosis with atrophy. S., See Charcot's Disease . S. o ium. Synonym of Osteitis, Condensing. S., Posterior Spinal, locomotor ataxia; tabes dorsal is, q. v. S., Postero-lateral. See Friedreich 's Ataxia. S., Progre ive Muscular. Synonym of Pseudo hypertrophic Muscular Paralysis. S., Renal. Synonym of Xephritis, Interstitial. S., Syphilitic Arterio-, the arterial sclerosis due to syphilis. It affects chiefly the intima, but also the adventitia. It occurs as a diffuse form, as in the brain; also in distinctly localized lesions, as in the chancre.