Atropia, Sul′phate of

Syn. Atro′pia sul′phas , L. Prep. (B. P.) Take of atropia, 120 gr. ; distilled water, 4 fl. dr. ; diluted sulphuric acid, a sufficiency. Mix the atropia with the water and add the acid gradually, stirring them together until the alkaloid is di olved and the solution is neutral. Evaporate it to dryne at a temperature not exceeding 100°. Characters and Tests. —A colourle powder, soluble in water, forming a solution which is neutral to test-paper, and when applied to the eye dilates the pupil as the solution of atropia does. It leaves no ash when burned with free acce of air. Intended for external application. It is a powerful poison. Uses, . The same as those of the pure alkaloid.— Dose , 1 ⁄ 25 to 1 ⁄ 20 gr., either in solution or pills; 1 to 3 gr. to water 1 fl. oz., as a collyrium, of which a few drops seldom fail to produce full dilation of the pupil in about a quarter of an hour; 1 to 2 gr. to lard 1 dr. forms an excellent ointment in neuralgic affections. Obs. Sulphate of atropia (which is intended for external use only) is rather difficult to crystallise, as it has a tendency to a ume an amorphous or gum-like condition. It is more soluble than the pure alkaloid; and, like it, is a terrific poison.