Extract of Nux Vom′ica

Syn. Extract of koochla nuts ; Extractum nucis vomicæ, B. P. Prep. 1. (Aqueous; E. n. v. Aquosum , L.—Ph. Bor.) From the powdered nut, as EXTRACT OF HOPS —Ph. L. (nearly.)— Dose , 1 to 5 gr. 2. (Alcoholic; Extractum nucis vomicæ —Ph. L. E. and D., E. n. v. alcohol i cum , L.)— a. (B. P.) Soften nux vomica by steam, dry rapidly, and reduce to fine powder; boil with rectified spirit until exhausted, strain, distil off the spirit, and evaporate to the consistence of a soft extract.— Dose , 1 ⁄ 2 to 2 gr. b. (Ph. L.) Koochla or poison nuts (seed or fruit of Strychnos Nux-vomica ), 8 oz.; rectified spirit, 3 pints; expose them to steam until softened, then bruise, slice, and dry them, and macerate them in 2-3rds of the spirit for 7 days; expre the tincture, and repeat the maceration with the remaining 1-3rd of the spirit; again expre the liquid; lastly, filter the mixed tinctures, distil off the greater part of the spirit, and complete the evaporation by a gentle heat. The formula of the P. Cod. is similar, but using spirit sp. gr. ·863 (=41 o. p.). c. (Ph. E.) The sliced and dried nuts are to be ground in a coffee-mill, and either exhausted by percolation with rectified spirit or by boiling the powder in repeated portions of the menstruum. The formulæ of the Ph. Baden and U. S. are similar. d. (Ph. D. 1826.) From a tincture of the rasped nut made with proof spirit, observing that the extract, whilst thickening, should be properly stirred. Obs. This extract consists chiefly of impure i gas urate of strychnia, and is exhibited in similar cases to that alkaloid. Used as a stimulant of the nervous system in paralysis.— Dose , 1 ⁄ 2 gr., gradually and cautiously increased to 2 gr. It is very poisonous. On the large scale, the nuts are ground in a drug-mill.