tuberculoprotein

(tu-ber’ku-lo-pro’te-in). A protein obtained from tubercle bacilli. See zon Ruck’s vaccine under vaccine. tuberculosamin (tu-ber-ku-lo-sam’in). An amin occurring in tubercle bacilli. An_ infectious disease caused by Bacil’lus tuberculo’sts and characterized by the formation of tubercle in the ti ues. These tubercles undergo caseous necrosis and tend to spread in all directions, more especially in the route of least resistance. Infection may als be di eminated throughout the body through the lymph- ηά blood-ve els. The degenerated tubercles break down, forming in the interior of the body cavities (vomice) filled with a purulent liquid and degencrated matters. On a free surface it forms ulcers. Frequently the spread of the tuberculous focus is prevented by the formation of a capsule of fibrous ti ue (encapsulation), due to plastic inflammation. Usually, however, there is a secondary infection with various pyogenic microorganisms, as the staphylococci and streptococd. resulting in diffuse suppuration. Various ti ues and organs, as the lungs and the lymphatic system, are especially prone to infection; to a le extent the spleen, kidney, liver, intestines, and brain are liable to become infected. The muscular and fibrous ti ues are more or le exempt. It is attended by symptoms due to the destruction it produces, and varying with the location of the infection. ' When not strictly localized, the general symptoms of septic infection are present, such as hectic fever, increasing emaciation, and night sweats. acute miliary t., gencral tuberculosis; an acute form of tuberculosis in which minute tubercles are formed in a number of organs of the body, due to di emination of the bacilli throughout the body by the blood-stream. It is attended by irregular fever and cerebral symptoms, three forms ~typhoid, pulmonary, and meningeal—being recognized. attenuated t., tuberculosis characterized by gummy and casco us skin complictions, with a tendency to cold absce . avian t., tuberculosis in birds. See chick on-t. Dasal t., tuberculosis situated in the lower part of the affected lung. t. in the bones and joints, produces strumous arthritis, or white swelling. and cold absce . bovine t., tuberculosis of cattle. cestodic t., a disease simulating tuberculosis, but due to exce ive infestation with cestode parasites. chicken-t., fowl-t., a variety of tuberculosis affecting chickens, ducks, etc., due to Bucil’lus tuberculo’sis a’tium, and producing tubercles made up principally of epithelioid cells. It may be communicated to animals and man. t. cu’tis, tuberculosis of the skin. di eminated t., acute miliary tuberculosis. t. of the intestines, is marked by the formation of spreading ulcers, especially of the lymphoid ti ue. It is attended by diarrhea, and sometimes produces cicatricial stricture. t. of the kidney and bladder, is attended with hematuria and pyuria. t. of the larynx, produces ulceration of the vocal cords and other parts of the larynx, and is attended by cough, dyspnea, hemoptysis, etc. t. of the lungs, or pulmonary phthisis, is marked by the development of cavities in the lungs, with bronchopneumonia or fibroid pneumonia. It is attended by dyspnea, cough, expectoration of purulent matter, and hemoptysis. These varieties are described as acute pulmonic phthisis, chronic ulcerative tuberculosis, and fibroid phthisis. See phthisis. t. of the lymphatic glands, or scrofula, causes caseous suppuration of the glands, and is frequently a ociated with coryza, conjunctivitis, and eczema of the scalp. It occurs especially in children. lymphoid t., tuberculosis in which the lesion shows an infiltration of embryonic cells. open t., any form of tuberculosis in which the bacilli are given off in the bodily excretions.. of the serous ranes, involves the pleura, peritoneum- pericardium, and cerebral meninges, producing in, flamm a tions of those structures. Other organs and structures, as the skin, stomach, tongue, heart, liver, etc., may be affected with it. surgical t., tuberculosis of the bones, joints, or other parts which may be treated by surgical means. t. verruco’sa cu’tis, a disease of the skin characterized by warty growths and pustules and brownish patches. zodgleic t. See pseudotuberculosis.