guanidinesulphocyanate

Chem.: CHN HCNS. This salt is easily prepared by heating ammonium sulphocyanate to between 180° and 190° for twenty hours, in a flask over a flame, with a long tube to carry off the vapors. It is then di olved in its own weight of cold water, filtered, and concentrated by evaporation on a water bath. On cooling, it deposits crystals of guanidine-sulphocyanate, which melt at 118°. Substitution compounds of guanidine are obtained by heating cyanamide with the hydro chlorates of primary amines, CN.NH2+NH2 CH3 HCl= CN3H4(CH3) HCl. Methyl-guanidine is also obtained by boiling creatine with mercuric oxide and water. Triethyl-guanidine, CN3H2(C2H5)3, is obtained by boiling an alcoholic solution of diethyl thio-carbamide and ethylamine with mercuric oxide. Diphenyl-guanidine is obtained by the action of gaseous cyanogen chloride on dry aniline, and also by boiling cyananilide with aniline hydro chlorate. It crystallizes in needles, which melt at 147°.