Lesion

(le’-zhwt) \_lcesio; Icedere, to hurt]. An injury, wound, or morbid structural change. L., Focal, in the nervous system, a circumscribed lesion giving rise to distinctive and localizing symptoms. L., Initial, of Syphilis, the chancre. L., Irritative, in the nervous system, a lesion exciting the functions of the part wherein it is situated. L., Peripheral, a lesion of the nerve-trunks or of their terminations. L., Primary, of the Skin, the change in the skin occurring in the developing stage of a skin-disease. L., Secondary. I. In the skin, the change occurring in the primary lesion, due to irritation or other causes. It comprises erosions, ulcers, rhagades, squamae, cicatrices or scars, crusts, and pigmentation. 2. One of the secondary manifestations of syphilis. 359