Acrodynia

(ak-ro-tlin'-f --nit). Epidemic erythema; a disease closely allied to pellagra. It is characterized by gastro-intestinal symptoms, redne of the conjunctivas, edema of the face, formication, pricking pains in the palm and soles, hyperesthesia followed by anesthesia of these parts, and an erythematous eruption preceded by bullae, chiefly on the hands and feet, but spreading over the limbs and trunk. This is followed by exfoliation and dark brown or black pigmentation, greatest in the warm regions of the body. Wasting of the limbs, with edema, cramps, pareses, and spasms may be present, and death may follow in the old or feeble. The disease is probably due to some noxious constituent of or defect in the diet.